Article

Beware the lymphopenia: a case of severe combined immunodeficiency.

Department of Allergy and Immunology, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.
Journal of Paediatrics and Child Health (impact factor: 1.28). 08/2011; 47(8):565-7. DOI:10.1111/j.1440-1754.2010.01870.x pp.565-7
Source: PubMed

ABSTRACT We present a case of a 2-month-old boy with partially treated meningitis and suspected Pneumocystis carinii pneumonia. A full blood count revealed profound lymphopenia. The child was diagnosed with adenosine deaminase deficiency, a rare cause of severe combined immunodeficiency (SCID). SCID is an immunological emergency and must be considered in any lymphopaenic infant with opportunistic infection. We discuss adenosine deaminase-deficient SCID, which can involve multiple systems and in which other treatment options apart from bone marrow transplant are available.

0 0
 · 
0 Bookmarks
 · 
54 Views
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

2-month-old boy
 
adenosine deaminase deficiency
 
adenosine deaminase-deficient SCID
 
bone marrow transplant
 
immunological emergency
 
lymphopaenic infant
 
opportunistic infection
 
Pneumocystis carinii pneumonia
 
profound lymphopenia
 
rare cause