Article

SEOM clinical guidelines for hereditary cancer.

High Risk and Cancer Prevention Unit, Medical Oncology Department, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.
Clinical and Translational Oncology (impact factor: 1.33). 08/2011; 13(8):580-6. DOI:10.1007/s12094-011-0701-2
Source: PubMed

ABSTRACT Research in genetics has facilitated the identification of highly penetrant genes responsible for a large number of diseases. In the oncology field, genetic counselling and gene testing are focused on the two most common syndromes in familial cancer: hereditary breast and ovarian cancer syndrome (HBOC) and hereditary non-polyposis colorectal cancer or Lynch syndrome (LS). The objective of this guideline in hereditary cancer is to summarise the current state of knowledge and make recommendations in the areas of diagnosis, prevention and treatment of hereditary cancer.

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Keywords

common syndromes
 
current state
 
diseases
 
familial cancer
 
genetic counselling
 
HBOC
 
hereditary breast
 
hereditary cancer
 
hereditary non-polyposis colorectal cancer
 
Lynch syndrome
 
ovarian cancer syndrome
 
penetrant genes responsible