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Organic Electrochemical Transistors Integrated in Flexible Microfluidic Systems and Used for Label-Free DNA Sensing

Department of Applied Physics and Materials Research Centre, The Hong Kong Polytechnic University, Hong Kong, China.
Advanced Materials (Impact Factor: 15.41). 09/2011; 23(35):4035-40. DOI: 10.1002/adma.201102017
Source: PubMed

ABSTRACT Organic electrochemical transistors are integrated in flexible microfluidic systems. A novel label-free DNA sensor is developed based on devices with single-stranded DNA probes immobilized on gate electrodes. These devices successfully detect complementary DNA targets at low concentrations using a pulse-enhanced hybridization technique in microfluidic channels. Organic electrochemical transistors are excellent candidates for flexible, highly sensitive, and low-cost biosensors.

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