Does tobacco smoke cause breast cancer?

Department of Public Health, University of Tennessee, 1914 Andy Holt Avenue, HPER 390, Knoxville, TN 37996, USA. .
Women s Health 07/2011; 7(4):405-8. DOI: 10.2217/whe.11.39
Source: PubMed
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    • "Breast cancer is the main cause of cancer death in women in Europe [2] and worldwide [3]. The incidence of breast cancer is increasing due to a number of factors, including improved diagnosis as a result of the expanded use of mammographic screening, an aging population [4], postmenopausal hormone replacement therapy [4] [5], obesity [4] [6] and alcohol [7] and tobacco consumption [8] [9]. "
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    ABSTRACT: To measure the impact of MammaPrint on adjuvant treatment decisions and to analyze the agreement in treatment decisions between hospitals from 4 European countries for the same patient cohort. Breast cancer patients were prospectively enrolled and MammaPrint was assessed. Patients' clinical data without and then with MammaPrint results were sent to the different multidisciplinary teams and treatment advice was provided for each patient. Using MammaPrint, chemotherapy treatment advice for ER+/HER2- breast cancer patients was changed in 37% of patients by the Dutch, 24% by the Belgian, 28% by the Italian and 35% by the Spanish teams. MammaPrint increased the inter-institutional agreement in treatment advice (chemotherapy or no chemotherapy) from 51% to 75%. The results of this study indicate that MammaPrint impacts adjuvant chemotherapy recommendation. MammaPrint can decrease inter-institutional and inter-country variability in adjuvant treatment advice for breast cancer patients.
    Breast (Edinburgh, Scotland) 03/2014; 23(4). DOI:10.1016/j.breast.2014.02.011 · 2.38 Impact Factor
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    • "Current smoking was also found to be associated with a higher likelihood of requiring follow up. As there is insufficient evidence to support a link between breast cancer and tobacco the reasons for this finding is not clear and is deserving of further study [19]. "
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    ABSTRACT: Mobile health units are increasingly utilized to address barriers to mammography screening. Despite the existence of mobile mammography outreach throughout the US, there is a paucity of data describing the populations served by mobile units and the ability of these programs to reach underserved populations, address disparities, and report on outcomes of screening performance. To evaluate the association of variables associated with outcomes for women undergoing breast cancer screening and clinical evaluation on a mobile unit. Retrospective analysis of women undergoing mammography screening during the period 2008-2010. Logistic regression was fitted using generalized estimating equations to account for potential repeat annual visits to the mobile unit. In total, 4,543 mammograms and/or clinical breast exams were conducted on 3,923 women with a mean age of 54.6, 29 % of whom had either never been screened or had not had a screening in 5 years. Age < 50 years, lack of insurance, Hispanic ethnicity, current smoking, or having a family relative (<50 years of age) with a diagnosis of cancer were associated with increased odds of a suspicious mammogram finding (BIRADS 4,5,6). Thirty-one breast cancers were detected. The mobile outreach initiative successfully engaged many women who had not had a recent mammogram. Lack of insurance and current smoking were modifiable variables associated with abnormal screens requiring follow up.
    Journal of Community Health 05/2013; 38(5). DOI:10.1007/s10900-013-9696-7 · 1.28 Impact Factor
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    ABSTRACT: Cancer is a leading global cause of death and disability, responsible for approximately 7.6 million deaths each year. Around one-third of cancers are attributable to a small number of preventable risk factors - including smoking and the harmful consumption of alcohol - for which effective interventions exist at the population level. Despite this, progress in global cancer control has been slow and patchy, largely due to the weak and fragmented nature of both the global and national responses. This has been exacerbated by the economic crisis and the tendency for other challenges involving food, energy security and climate change to overshadow cancer on the global policy agenda. This paper reviews the global burden of cancer, and summarizes knowledge about effective interventions. Responding to the global challenge of cancer requires a comprehensive and integrated approach that includes legislation and regulation. A re-invigorated approach to global cancer prevention, within the broader context of non-communicable disease prevention, is an important pathway to global health and development.
    Public health 12/2011; 125(12):821-31. DOI:10.1016/j.puhe.2011.09.029 · 1.43 Impact Factor
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