Sialoblastoma- long-term follow-up and remission for a rare salivary malignancy

Montefiore Medical Center, New York, NY
Rare tumors 04/2011; 3(2):e13. DOI: 10.4081/rt.2011.e13
Source: PubMed


Sialoblastoma is a rare salivary neoplasm which presents either congenitally or during early infancy. It was originally considered a benign neoplasm, however a number of reported cases have documented locoregional recurrence and distant metastases. Currently, there is no consensus on the appropriate treatment for this neoplasm. We report on long term follow-up of a patient with metastatic sialoblastoma, and a brief discussion of the possible treatment modalities currently being considered.

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Available from: Kanwal M Farooqi, Dec 17, 2013
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    • "In one case sex has not been mentioned. 31 tumour were related to parotid,[37891011121314151617181920212223242526272829] 11 submandibular,[121830313233343536] two cheek minor salivary gland,[537] one was in relation with eyelid minor salivary gland[38] and one presented as face and neck mass[39] [Tables 1 and 2] "
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    ABSTRACT: Sialoblastoma is a rare congenital tumour of the salivary glands arising mainly from the parotid gland. It is usually diagnosed at birth or shortly thereafter with a significant variability in histological appearance and clinical course. In extensive search of PubMed indexed journals, we got 46 cases of "sialobalstoma/embryoma/congenital basal adenoma", with one case was of German literature and three additional cases of adult sialobalstoma. This article has extensively reviewed the clinical, histopathological and immunohistochemical features, Magnetic resonance imaging (MRI) and Computerized Tomography (CT) findings, treatment and prognosis.
    03/2013; 4(1):13-18. DOI:10.4103/0975-5950.117821
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    ABSTRACT: To evaluate outcome of surgical excision of sialoblastoma in the parotid gland in newborn. This was a retrospective review of 3 pediatric patients with sialoblastoma in the parotid gland that underwent surgical resections. All patients are newborn boys. The lesions ranged from 5cm×5cm to 8cm×5cm in size. The tumor was resected en bloc, and the facial nerve was preserved. None surgical complications occurred. The mean follow-up was 34 months; none patients had recurrent lesions. Surgical dissection of sialoblastoma in the parotid gland in the newborn is most efficient and safe.
    International journal of pediatric otorhinolaryngology 06/2013; 77(8). DOI:10.1016/j.ijporl.2013.05.006 · 1.19 Impact Factor
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    ABSTRACT: Background Sialoblastoma is an extremely rare congenital salivary gland tumor of epithelial origin. It is usually localized in the parotid or submandibular gland and presents primarily at birth or in early childhood.Methods We report a case of a 13-year-old female with a sialoblastoma of the parotid gland presenting as an asymptomatic painless mass.ResultsThe patient showed multiple recurrences and, based on the histopathological finding of facial nerve infiltration, was treated surgically with total parotidectomy and facial nerve reconstruction.Conclusion Due to the rare occurrence of sialoblastoma, there is no evidence-based treatment of choice. The treatment should be individualized, taking into consideration the patient's age, the high locoregional recurrence rate, the local aggressive characteristics and the potential metastatic activity of this rare tumor. A close follow-up of the patient is strongly recommended. This article is protected by copyright. All rights reserved.
    Head & Neck 04/2015; DOI:10.1002/hed.24084 · 2.64 Impact Factor