Background prevalence of extended-spectrum β-lactamase-producing Enterobacteriaceae in the Auckland community

Labtests, Auckland, New Zealand. .
The New Zealand medical journal 04/2011; 124(1332):102-4.
Source: PubMed
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    ABSTRACT: Antimicrobial resistance is one of the biggest health threats of the modern age, threatening the routine treatment of many common infectious diseases. Resistance to many common antimicrobials is now endemic in New Zealand, in both community and healthcare settings. Over the past two decades, the landscape of antimicrobial resistance has changed considerably in New Zealand, with the emergence and spread of pathogens such as community-associated methicillin-resistant Staphylococcus aureus, extended-spectrum ?-lactamase-producing Enterobacteriaceae and multi- resistant Neisseria gonorrhoeae. Factors contributing to the emergence and spread of antimicrobial-resistant pathogens in New Zealand include the use and overuse of antimicrobials, transmission of resistant organisms in community and healthcare settings, and importation of resistant pathogens from areas where multi-resistant pathogens are endemic. In this review, we provide a summary of major antimicrobial-resistant bacteria in New Zealand, with a specific focus on those pathogens that pose major threats to human health.
    The New Zealand medical journal 10/2014; 127(1403):41-54.
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    ABSTRACT: INTRODUCTIONThe aim of this study was to detect the prevalence of the extended-spectrum beta-lactamase (ESBL)-encoding CTX-M gene in Escherichia coliisolates. Phenotypic screening of 376 E. coli isolates for ESBL was conducted using disk diffusion. ESBL-producing isolates were tested using PCR and specific primers. The blaCTX-M cluster was identified using the RFLP method, and its genotype was sequenced. From 202 ESBL-producing E. coli , 185 (91.5%) possessed CTX-M genes. CTX-M-1 subtypes were found in 98% of the isolates. The blaCTX-M gene was identical to CTX-M-15. A high prevalence of CTX-M-1-producing E. coli apparently exists in Shiraz, Iran.
    Revista da Sociedade Brasileira de Medicina Tropical 08/2015; 48(4):479-82. DOI:10.1590/0037-8682-0315-2014 · 0.98 Impact Factor

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