Prevalence of self-report photosensitivity in cutaneous lupus erythematosus

Philadelphia Department of Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA.
Journal of the American Academy of Dermatology (Impact Factor: 5). 07/2011; 66(2):220-8. DOI: 10.1016/j.jaad.2010.12.006
Source: PubMed

ABSTRACT Little is known about the prevalence of self-reported photosensitivity (PS) and its effects on quality of life in a US cutaneous lupus population.
We sought to determine the prevalence of self-reported PS among a cutaneous lupus population and to examine its impact on quality of life.
A total of 169 patients with lupus were interviewed about PS symptoms and completed the modified Skindex-29+3, a quality-of-life survey. A complete skin examination was conducted and the Cutaneous Lupus Erythematosus Disease Area and Severity Index was completed.
In all, 68% of patients reported some symptoms of PS. The PS group (those who reported a history of and current PS) scored worse on PS-related items of the modified Skindex-29+3 and had higher cutaneous disease activity as determined by the Cutaneous Lupus Erythematosus Disease Area and Severity Index. Patients with PS had worse symptoms and emotions and experienced significant functional impairments compared with patients who had cutaneous lupus without PS.
This study was done at a single referral center.
Self-reported PS is very common among patients with cutaneous lupus and is associated with significant impairments related to symptoms, emotions, and daily functioning.

  • [Show abstract] [Hide abstract]
    ABSTRACT: Patients with lupus erythematosus (LE) are often abnormally photosensitive. Ultraviolet (UV) exposure can not only induce cutaneous lesions but may also contribute to systemic flares and disease progression. Various forms of energy-efficient lighting have been shown to emit UV radiation. To determine the effects of these emissions on individuals with LE. This assessment investigated cutaneous responses to repeated exposures from three types of lighting: compact fluorescent lamp (CFL), light-emitting diode (LED) and energy-efficient halogen (EEH). The subjects were 15 patients with LE and a control group of five healthy volunteers. No cutaneous LE lesions were induced by any of the light sources. Delayed skin erythema was induced at the site of CFL irradiation in six of the 15 patients with LE and two of the five healthy subjects. Erythema was increased in severity and more persistent in patients with LE. One patient with LE produced a positive delayed erythema to the EEH. A single patient with LE produced immediate abnormal erythemal responses to the CFL, LED and EEH. Further investigation revealed that this patient also had solar urticaria. All other subjects had negative responses to LED exposure. Compact fluorescent lamps emit UV that can induce skin erythema in both individuals with LE and healthy individuals when situated in close proximity. However, this occurs to a greater extent and is more persistent in patients with LE. EEHs emit UVA that can induce erythema in patients with LE. LEDs provide a safer alternative light source without risk of UV exposure.
    British Journal of Dermatology 03/2014; 170(3):694-8. DOI:10.1111/bjd.12719 · 3.76 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Cutaneous Lupus Erythematosus (CLE) and Dermatomyositis (DM) are cutaneous autoimmune diseases that have been among the least systematically studied, due in part to the lack of validated outcome instruments in the past. More recent epidemiologic studies have elucidated the incidence and prevalence of these diseases and their subtypes. In addition, the advent of validated clinical outcome measures, including the Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI) and the Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI), has led to an objective means of measuring activity and damage of the disease. These outcome measures have established the framework for evaluating responsiveness and therapeutic efficacy in clinical trials as well as longitudinal studies to study disease course.
    03/2013; 2(1). DOI:10.1007/s13671-012-0037-3
  • [Show abstract] [Hide abstract]
    ABSTRACT: The present research note is an extension of previous study which used a survey method to investigate barriers to garden visitation in five children's hospitals in Texas. In previous study, we found that lack of shade and comfortable seats will significantly reduce duration of garden visitation for staff, and inadequate shade significantly reduces duration and frequency of garden visitation for visitors and patients. With the findings from previous study, we used scores from garden shade maps in conjunction with scores from available hospital garden audit tools (which measured quality of garden seats, plants, layout, and amenities for children, and location) to evaluate the same five hospital gardens. Through an exploratory data analysis strategy, the gardens were scored and ranked based on their design characteristics, reported garden use, and observed garden use. The general agreement observed between these rankings suggested that quality of design, can influence levels of physical activity in pediatric hospital gardens.
    Landscape and Urban Planning 10/2013; 118:53-58. DOI:10.1016/j.landurbplan.2013.05.005 · 2.61 Impact Factor

Full-text (2 Sources)

Available from
Oct 2, 2014