Article

Association between urinary arsenic and diabetes mellitus in the Korean general population according to KNHANES 2008.

Department of Occupational and Environmental Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea.
Science of The Total Environment (impact factor: 3.29). 06/2011; 409(19):4054-62. DOI:10.1016/j.scitotenv.2011.06.003 pp.4054-62
Source: PubMed

ABSTRACT We present data from the Korean National Health and Nutrition Examination Survey (KNHANES) 2008 on the associations between urinary arsenic and diabetes mellitus in a representative sample of the adult Korean population.
This study was based on data obtained in KNHANES 2008, which was conducted for three years (2007-2009) using a rolling sampling design involving a complex, stratified, multistage, probability-cluster survey of a representative sample of the noninstitutionalized civilian population of South Korea.
Geometric means of total urinary arsenic concentration in females and total participants with diabetes mellitus were significantly higher than in participants without diabetes mellitus after adjustment for covariates, including age, seafood consumption, body mass index (BMI), hypertension, area of residence, regional area, education level, and smoking and drinking status. Multiple regression analysis after similar adjustment showed that total urinary arsenic concentration was associated with diabetes status in the females and total participants. In addition, after similar adjustment, the odds ratios (ORs) for diabetes mellitus in female participants and all participants were 1.502 (95% CI, 1.038-2.171) and 1.312 (95% CI, 1.040-1.655), respectively, for doubling of the level of urinary total arsenic concentration.
This study showed an association between total urinary arsenic concentration and the prevalence of diabetes mellitus in a representative sample of the adult population, especially women, with environmental arsenic exposure after adjustment for seafood intake and relevant diabetes risk factors.

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    Article: Exposure to low level of arsenic and lead in drinking water from Antofagasta city induces gender differences in glucose homeostasis in rats.
    Javier Palacios, Domingo Roman, Fredi Cifuentes
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Keywords

adult Korean population
 
body mass index
 
diabetes status
 
drinking status
 
education level
 
environmental arsenic exposure
 
Korean National Health
 
Multiple regression analysis
 
multistage
 
noninstitutionalized civilian population
 
Nutrition Examination Survey
 
probability-cluster survey
 
regional area
 
relevant diabetes risk factors
 
rolling sampling design
 
seafood intake
 
similar adjustment
 
total urinary arsenic concentration
 
urinary arsenic
 
urinary total arsenic concentration
 

Yangho Kim