Long-Term Survival in a Rare Case of Malignant Esophageal Schwannoma Cured by Surgical Excision

Department of Thoracic Surgery, First Affiliated People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
The Annals of thoracic surgery (Impact Factor: 3.65). 07/2011; 92(1):357-8. DOI: 10.1016/j.athoracsur.2011.01.045
Source: PubMed

ABSTRACT A full account is presented of a 44-year-old woman with an extremely rare case of a malignant esophageal schwannoma that had been misdiagnosed as a leiomyoma 3 years earlier. After surgical enucleation, the patient has survived for 6 years without any adjunctive treatment.

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    ABSTRACT: Esophageal schwannoma is a rare tumor first described in 1967 by Chaterlin and Fissore. These tumors are most commonly found incidentally or from diagnostic work up of dysphagia or dyspnea. This entity cannot be diagnosed on clinical or radiographic basis alone. Histology demonstrates palisading spindle cells, few if any mitotic figures, and a peripheral cuff of lymphoid cells. Immunohistochemically, tumor cells stain positive for S100, a characteristic marker of Schwann cells. Once diagnosed, surgical enucleation is the typical treatment method employed.
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