[Epidemiological and clinical significance of hepatitis B and C marker detection in blood of patients and donors].
ABSTRACT During the assessment of 118 299 patients from hospital n. a. A.A.Vishnevskiy (2001-2005) anti-HCV was found out in 3.6%, HbsAg in 1.94%. By comparison with data of 1992-1994 (hospital n. a. N.N.Burdenko) the indices of disclosure of anti-HCV in in-patients fell 2 times, HbsAg 6.4 times. During this period, diverse changes of frequency of detection of markers in blood-donors took place: HbsAg--reduction, anti-HCV-elevation. During 2001-2005 reduction of frequency of detection of anti-HCV was noted in in-patients and blood donors, but reduction of frequency of detection of HbsAg only in blood donors. The frequency of detection of hepatitis C, B markers in blood donors during the last 10-15 years is correlated with the incidence of virus cirrhosis. Dynamic changes or stability of frequency of detection of hepatitis C, B markers in blood donors and in-patients during current period is correlated with the score of virus cirrhosis mortality.