Article

Impact of Policy Change on US Army Combat Transfusion Practices

United States Army Institute of Surgical Research, Fort Sam Houston, Texas 78234, USA.
The Journal of trauma (Impact Factor: 2.96). 07/2010; 69 Suppl 1(Supplement):S75-80. DOI: 10.1097/TA.0b013e3181e44952
Source: PubMed

ABSTRACT BACKGROUND: Clinical practice guidelines (CPGs) are used to keep providers up-to-date with the most recent literature and to guide in decision making. Adherence is typically improved although many have a muted impact. In March 2006, the US Army issued a damage control resuscitation CPG, encouraging 1:1 plasma:red blood cell (RBC) transfusions and limiting crystalloid use. The objective of this study was to determine whether the CPG was associated with a change in the transfusion practices in combat-wounded patients.

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    • "The MTP published by Dirks et al. resulted in a significant increase in PC transfusion without any improvement in the survival rate [55]. Similar results were reported by Simmons et al., who observed that the introduction of new clinical practice guidelines forcing early platelet transfusion resulted in no survival benefit [54]. Thus, platelet transfusion in a fixed predefined ratio carries the potential for wasting valuable resources and the risk of complications (e.g. "
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    Scandinavian Journal of Trauma Resuscitation and Emergency Medicine 02/2012; 20(1):15. DOI:10.1186/1757-7241-20-15 · 1.93 Impact Factor
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