Article

Reflex conditioning: a new strategy for improving motor function after spinal cord injury.

New York State Department of Health, Wadsworth Center, Albany, New York 12201-0509, USA.
Annals of the New York Academy of Sciences (impact factor: 3.15). 06/2010; 1198 Suppl 1:E12-21. DOI:10.1111/j.1749-6632.2010.05565.x pp.E12-21
Source: PubMed

ABSTRACT Spinal reflex conditioning changes reflex size, induces spinal cord plasticity, and modifies locomotion. Appropriate reflex conditioning can improve walking in rats after spinal cord injury (SCI). Reflex conditioning offers a new therapeutic strategy for restoring function in people with SCI. This approach can address the specific deficits of individuals with SCI by targeting specific reflex pathways for increased or decreased responsiveness. In addition, once clinically significant regeneration can be achieved, reflex conditioning could provide a means of reeducating the newly (and probably imperfectly) reconnected spinal cord.

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Keywords

Appropriate reflex conditioning
 
clinically significant regeneration
 
induces spinal cord plasticity
 
new therapeutic strategy
 
reflex conditioning
 
SCI
 
specific deficits
 
specific reflex pathways
 
spinal cord injury
 
Spinal reflex conditioning changes reflex size