Cervical Cancer Incidence, Mortality, and Survival Among Asian Subgroups in California, 1990-2004

Public Health Institute, California Cancer Registry, Sacramento, California 95825, USA.
Cancer (Impact Factor: 4.9). 11/2008; 113(10 Suppl):2955-63. DOI: 10.1002/cncr.23752
Source: PubMed

ABSTRACT Aggregated cancer statistics for Asians mask important differences in cancer burden among Asian subgroups. The purpose of this study was to describe the relative patterns of cervical cancer incidence, mortality, and survival among Chinese, Filipino, Japanese, Korean, South Asian, and Vietnamese women in California, using data from the California Cancer Registry.
All cervical cancer cases diagnosed among the 6 subgroups and non-Hispanic whites (NHW) from 1990 to 2004 were identified and used to calculate incidence and mortality rates and trends. The Kaplan-Meier method was used to calculate 5- and 10-year survival probabilities by subgroup, and Cox proportional hazards methodology was used to calculate survival differences adjusted for race and ethnicity, age, stage at diagnosis, socioeconomic status, and treatment factors.
Vietnamese and Korean women experienced greater cervical cancer incidence and mortality than NHW women, whereas rates among Chinese, Japanese, and South Asians were comparable or lower. Five-year unadjusted survival probabilities were greatest for South Asians (86%) and Koreans (86%), followed by Vietnamese (82%), Chinese (79%), and Filipinos (79%), as compared with NHW (78%) and Japanese (72%). The adjusted risk of cervical cancer death was significantly lower for South Asians, Koreans, Vietnamese, and Filipinos than for NHW women, but not for Chinese and Japanese.
Cervical cancer incidence rates vary substantially across the major Asian subgroups. Despite higher incidence and mortality rates compared with NHW women, Vietnamese, Koreans, and Filipinos have better survival outcomes. Further studies are needed to examine the factors behind these survival differences.

  • [Show abstract] [Hide abstract]
    ABSTRACT: Research on the incidence of cancer among the immigrant population has tended to be of quite a limited scope. We investigate whether immigrant women in the US are less likely to have been recently diagnosed with cancer, and what factors might help to explain any differences identified. We estimate multivariate Logistic regression models to identify the determinants of a diagnosis within the last 3years of any cancer, of breast cancer and of cervical cancer as well as the use of cancer screening by US women, using self-reported information on cancer diagnosis from consecutive waves of the US National Health Interview Survey over the years 1998–2007. Immigrant women of different ethnic groups are less likely to have been diagnosed with cancer, breast cancer and cervical cancer compared to US-born women. The use of basic health services, including cancer screening, is also lower for immigrant women for each main ethnic group. More research is required to determine whether immigrants may face delays in timely diagnosis of cancer by health care professionals. KeywordsCancer–Immigrant health–Minority women–Breast cancer–Cervical cancer–Cancer screening
    Journal of Immigrant and Minority Health 02/2011; 13(1):27-35. DOI:10.1007/s10903-009-9268-1 · 1.16 Impact Factor
  • Source
    Cancer 11/2008; 113(10 Suppl):2837-40. DOI:10.1002/cncr.23753 · 4.90 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Survival for gastric cancer is reportedly higher in Asians than for other races. It is unclear whether differences in outcome exist among Asian ethnicities. Our objective was to assess gastric cancer survival in Asian ethnic groups in a large heterogeneous population. Asian-Americans treated for gastric adenocarcinoma between 1988 and 2006 were identified from the Los Angeles County Cancer Surveillance Program. Patients were stratified and compared by ethnicity (Korean, Japanese, Chinese, Vietnamese or Filipino). Of the 1,817 Asian-Americans in the study cohort, 45% (n = 810) were Korean, 25% (n = 462) were Chinese, 11% (n = 193) were Japanese, 10% (n = 188) were Filipino, and 9% (n = 164) were Vietnamese. For the entire cohort Koreans and Filipinos had the longest and shortest median survival (MS), respectively (22.4 and 10.3 months, respectively; P < 0.001). Multivariate analysis demonstrated that Japanese and Filipino ethnicity independently predicted worse survival compared with Korean ethnicity [hazard ratio (HR) 1.37, 95% confidence interval (CI) 1.08-1.73, P = 0.008; and HR 1.71, 95% CI 1.37-2.13, P < 0.001, respectively]. In the surgical cohort, Koreans and Filipinos had the longest and shortest survival, respectively (MS of 57.8 and 21.7 months, respectively; P < 0.001). Multivariate analysis of the surgical cohort also demonstrated that Japanese and Filipino ethnicity independently predicted worse survival compared with Korean ethnicity (HR 1.61, 95% CI 1.22-2.13, P < 0.001; and HR 1.66, 95% CI 1.24-2.22, P < 0.001, respectively). There are differences in gastric cancer survival among Asian ethnicities. Future studies addressing varying environmental exposures and molecular expression patterns in gastric cancer are warranted to better understand these disparities in outcome.
    Annals of Surgical Oncology 08/2009; 16(9):2433-41. DOI:10.1245/s10434-009-0584-4 · 3.94 Impact Factor