Article

Cerebrovascular diseases.

Department of Neurological Sciences, Viale dell' Università, 30, 00185 Rome, Italy.
Neurological Sciences (impact factor: 1.32). 10/2008; 29 Suppl 3:314-8. DOI:10.1007/s10072-008-1006-2 pp.314-8
Source: PubMed

ABSTRACT Conventional neuroradiological techniques, such as computed tomography (CT) and magnetic resonance imaging (MRI), make a fundamental contribution in both the acute and chronic phases of stroke. Recent years have witnessed the development of new imaging modalities, which include diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI), CT-angiography (CTA), MR-angiography (MRA), magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI) and functional MRI (fMRI). While CTA, MRA, DWI and PWI are commonly used for clinical purposes, DTI, MRS and fMRI are becoming increasingly important in the field of experimental research of cerebrovascular diseases, but are still far from becoming of primary usefulness in the everyday clinical setting.

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    Article: The use of MRI apparent diffusion coefficient (ADC) in monitoring the development of brain infarction.
    Jian-Min Shen, Xian-Wu Xia, Wu-Gen Kang, Jian-Jun Yuan, Liang Sheng
    [show abstract] [hide abstract]
    ABSTRACT: To study the rules that apparent diffusion coefficient (ADC) changes with time and space in cerebral infarction, and to provide the evidence in defining the infarction stages. 117 work-ups in 98 patients with cerebral infarction (12 hyperacute, 43 acute, 29 subacute, 10 steady, and 23 chronic infarctions) were imaged with both conventional MRI and diffusion weighted imaging. The average ADC values, the relative ADC (rADC) values, and the ADC values or rADC values from the center to the periphery of the lesion were calculated. The average ADC values and the rADC values of hyperacute and acute infarction lesion depressed obviously. rADC values in hyperacute and acute stage was minimized, and increased progressively as time passed and appeared as "pseudonormal" values in approximately 8 to 14 days. Thereafter, rADC values became greater than normal in chronic stage. There was positive correlation between rADC values and time (P < 0.01). The ADC values and the rADC values in hyperacute and acute lesions had gradient signs that these lesions increased from the center to the periphery. The ADC values and the rADC values in subacute lesions had adverse gradient signs that these lesions decreased from the center to the periphery. The ADC values of infarction lesions have evolution rules with time and space. The evolution rules with time and those in space can be helpful to decide the clinical stage, and to provide the evidence in guiding the treatment or judging the prognosis in infarction.
    BMC Medical Imaging 01/2011; 11:2. · 1.09 Impact Factor
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

cerebrovascular diseases
 
chronic phases
 
clinical purposes
 
computed tomography
 
Conventional neuroradiological techniques
 
CT-angiography
 
CTA
 
diffusion tensor imaging
 
DTI
 
DWI
 
experimental research
 
fMRI
 
fundamental contribution
 
include diffusion-weighted imaging
 
magnetic resonance imaging
 
magnetic resonance spectroscopy
 
new imaging modalities
 
perfusion-weighted imaging
 
primary usefulness