Cinnamon extracts' inhibitory effect on Helicobacter pylori.

M Tabak, R Armon, I Neeman

Food Engineering and Biotechnology Faculty, Technion, Haifa, Israel.

Journal Article: Journal of Ethnopharmacology (impact factor: 2.32). 11/1999; 67(3):269-77.

Abstract

Ethanol and methylene chloride extracts of cinnamon were compared for their effect on Helicobacter pylori growth and urease activity. Methylene chloride extract was found to inhibit growth of H. pylori, while ethanol extract counteracted its urease activity. Cinnamon extract (from methylene chloride) inhibited H. pylori at concentration range of common antibiotics. Complete inhibition in vitro was achieved by 50 microg/ml in solid medium (egg yolk emulsion agar) and by 15 microg/ml in liquid medium (supplemented brain heart infusion broth). The cinnamon extracts were more inhibitory on free urease than on whole cell urease.

Source: PubMed

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Keywords

Cinnamon
 
common antibiotics
 
counteracted
 
egg yolk emulsion agar
 
Ethanol
 
H. pylori
 
Helicobacter pylori growth
 
inhibitory
 
liquid medium
 
methylene chloride
 
supplemented brain heart infusion broth
 
vitro
 
whole cell urease