Television viewing and risk of type 2 diabetes, cardiovascular disease, and all-cause mortality: a meta-analysis.
ABSTRACT Prolonged television (TV) viewing is the most prevalent and pervasive sedentary behavior in industrialized countries and has been associated with morbidity and mortality. However, a systematic and quantitative assessment of published studies is not available.
To perform a meta-analysis of all prospective cohort studies to determine the association between TV viewing and risk of type 2 diabetes, fatal or nonfatal cardiovascular disease, and all-cause mortality.
Relevant studies were identified by searches of the MEDLINE database from 1970 to March 2011 and the EMBASE database from 1974 to March 2011 without restrictions and by reviewing reference lists from retrieved articles. Cohort studies that reported relative risk estimates with 95% confidence intervals (CIs) for the associations of interest were included.
Data were extracted independently by each author and summary estimates of association were obtained using a random-effects model.
Of the 8 studies included, 4 reported results on type 2 diabetes (175,938 individuals; 6428 incident cases during 1.1 million person-years of follow-up), 4 reported on fatal or nonfatal cardiovascular disease (34,253 individuals; 1052 incident cases), and 3 reported on all-cause mortality (26,509 individuals; 1879 deaths during 202,353 person-years of follow-up). The pooled relative risks per 2 hours of TV viewing per day were 1.20 (95% CI, 1.14-1.27) for type 2 diabetes, 1.15 (95% CI, 1.06-1.23) for fatal or nonfatal cardiovascular disease, and 1.13 (95% CI, 1.07-1.18) for all-cause mortality. While the associations between time spent viewing TV and risk of type 2 diabetes and cardiovascular disease were linear, the risk of all-cause mortality appeared to increase with TV viewing duration of greater than 3 hours per day. The estimated absolute risk differences per every 2 hours of TV viewing per day were 176 cases of type 2 diabetes per 100,000 individuals per year, 38 cases of fatal cardiovascular disease per 100,000 individuals per year, and 104 deaths for all-cause mortality per 100,000 individuals per year.
Prolonged TV viewing was associated with increased risk of type 2 diabetes, cardiovascular disease, and all-cause mortality.
- SourceAvailable from: Jan Sorensen[Show abstract] [Hide abstract]
ABSTRACT: BackgroundSedentary behavior has been recognized as a distinct and independent risk factor for cardiovascular morbidity and mortality, independent of moderate and vigorous physical activity during leisure time. Sedentary behavior has become increasingly prevalent in modern society. Patients with rheumatoid arthritis (RA) have an increased risk for cardiovascular disease and premature death, partly caused by the chronic inflammatory rheumatic disease itself, but also due to physical inactivity. Recent research has shown that sedentary behavior can be reduced through behavioral intervention in elderly and in overweight study populations.Background Patients with RA (Rheumatoid Arthritis) are more sedentary than the general population. Reduction of Sedentary Behaviour (SB) has been suggested as a mean for improvement of health in patients with chronic diseases and mobility problems. Short-term intervention studies have demonstrated that SB can be reduced by behavioural interventions in healthy populations. However, it remains unexplored whether it is valid for patients with RA also.Therefore, the aim of this trial is to investigate the efficacy of an individually tailored, theory-based motivational counseling intervention on reducing daily sitting time in sedentary patients with RA. Additionally, to explore whether a reduction in daily sitting time is associated with reduced pain and fatigue, self-reported physical function, self-efficacy, improved health-related quality of life (HRQoL) and cardiovascular biomarker levels, and finally to assess the cost-effectiveness of the intervention.Methods/DesignFor this parallel group randomized trial, 150 patients with RA and at least 5 hours of sitting time per day, will be recruited from a rheumatology outpatient clinic, and block-randomized to the intervention group or the control group receiving usual care. The intervention includes: 1) individual motivational counseling (in total 3 sessions) on reduction of daily sitting time in combination with 2) individual Short Text Message Service (SMS) reminders over a 16-week intervention period. Primary outcome is change in daily sitting time (minutes) from baseline to 16 weeks measured objectively using an ActivPAL® Activity Monitor. Secondary outcomes include fatigue, pain, physical function, HRQoL, self-efficacy, costs and cost-effectiveness. Furthermore, anthropometric measures will be included as well as measurement of blood pressure and serum lipids. All outcomes are assessed at baseline and repeated after 16 weeks. Follow-up assessments are made at 6 and 18 months post-intervention.DiscussionThe intervention is simple, non-invasive and may be implemented at low costs. If the study confirms the positive results expected, the intervention might be implemented in clinical practice and potentially transferred to other clinical populations.Trial registrationClinicalTrial.gov registration number: NCT01969604.Date of registration: 17 October 2013.Trials. 01/2015; 16(1):23.
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ABSTRACT: Time spent watching TV by Europeans has been calculated to be 22.1 hours per week on average and it has shown to be correlated with a series of physical and mental problems in adults. Very little research is available in population over 65. This study aimed at evaluating the association between TV viewing and mental disorders and cognitive performance, taking into account the general physical activity level and socio-demographic characteristics in Europe.Mental Health and Physical Activity 12/2014;
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ABSTRACT: Aim: To compare the cumulative (three-day) effect of prolonged sitting on metabolic responses during a mixed meal tolerance test (MTT), with sitting that is regularly interrupted with brief bouts of light-intensity walking. Research design and methods: Overweight/obese adults (n=19) were recruited for a randomized, three-day, outpatient, crossover trial involving: 1) 7-hour days of uninterrupted sitting (SIT); and, 2) 7-hour days of sitting with light-intensity activity breaks [BREAKS; 2-minutes of treadmill walking (3.2 km/hour) every 20 minutes (total: 17 breaks/day)]. On days 1 and 3, participants underwent a MTT (75g carbohydrate, 50g fat), and the incremental area under the curve (iAUC) was calculated from hourly blood samples. GEE models were adjusted for gender, BMI, energy intake, treatment order and pre-prandial values to determine effects of time, condition and time x condition. Results: The glucose iAUC was 1.3 ± 0.5 and 1.5 ± 0.5 mmol.hr.L-1 (mean difference ± SEM) higher in SIT compared with BREAKS on days 1 and 3 respectively (condition effect: P=0.001), with no effect of time (P=0.48) or time x condition (P=0.8). The insulin iAUC was also higher on both days in SIT (Day 1: ∆151 ± 73, Day 3: ∆91 ± 73 pmol.hr.L-1, P=0.01), with no effect of time (P=0.52) or time x condition (P=0.71). There was no between-treatment difference in triglycerides iAUC. Conclusion: There were significant between-condition effects but no temporal change in metabolic responses to MTT, indicating that breaking up sitting over three days sustains, but does not enhance, the lowering of postprandial glucose and insulin.Clinical science (London, England : 1979). 03/2015;