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Treat Alzheimer Disease Before It Is Symptomatic

University of Texas Southwestern Medical Center, Dallas.
Archives of neurology (Impact Factor: 7.01). 06/2011; 68(10):1237-8. DOI: 10.1001/archneurol.2011.135
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    • "There is emerging evidence that biomarkers, including brain imaging markers, represent prodromal characteristics that anticipate Alzheimer's disease, Huntington's disease, and Parkinson's disease (Aylward, Liu, Nopoulos, Ross, Pierson, Mills, Long, & Paulsen, 2012; Lo, Hubbard, Shaw, Trojanowski, Petersen, Aisen, Weiner, & Jagust, 2011; Rodriguez- Oroz, Jahanshahi, Krack, Litvan, Macias, Bezard, & Obeso, 2009; Tabrizi, Scahill, Durr, Roos, Leavitt, Jones, Landwehrmeyer, Fox, Johnson, Hicks, Kennard, Craufurd, Frost, Langbehn, Reilmann, & Stout, 2011). Prevention science and/or interventions designed to attenuate the progression of symptoms holds much promise for these conditions (Rosenberg, 2011; Schapira & Tolosa et al., 2010). In the current study, we present preliminary evidence that a brain imaging marker collected at 6 months of age predicts the performance level of an important social-cognitive behavior at 9 months of age. "
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