Molecular sensors and sensor arrays based on polyaniline microtubules
ABSTRACT This paper describes the fabrication of microtubular biosensors and sensor arrays based on polyaniline with superior transducing ability. These sensors have been tested for the estimation of glucose, urea, and triglycerides. As compared to that of a macro sensor, the response of the microtubular sensor for glucose is higher by a factor of more than 10(3). Isoporous polycarbonate membranes have been used to fabricate inexpensive devices by simple thermal evaporation of gold using appropriate machined masks. Polyaniline deposition and enzyme immobilization have been done electrochemically. Electrochemical potential control has been used to direct enzyme immobilization to the chosen membrane device and avoid cross talk with adjacent devices. This has enabled the immobilization of a set of three different enzymes on three closely spaced devices, resulting in a microtubule array that can analyze a sample containing a mixture of glucose, urea, and triglycerides in a single measurement. This, in essence, is an "electronic tongue".
SourceAvailable from: Mohit Saraf[Show abstract] [Hide abstract]
ABSTRACT: Styrene sulphonic acid (SSA) doped polyaniline (PAni) was chemically synthesized.•SSA-Pani was treated with 3-(aminopropyl) triethoxysilane to activate −NH2 group.•SSA-PAni modified carbon electrode is bioconjugated with anti-atrazine antibodies.•Atrazine immunosensor offers highly sensitive specific detection of atrazine.•Limit of detection is 0.01 ng/mL. Range of analysis is 0.01–50 ng/mL.Electrochimica Acta 09/2014; DOI:10.1016/j.electacta.2014.09.048 · 4.09 Impact Factor
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ABSTRACT: Nanocolloidal poly(aniline-co-o-toluidine) particles were synthesized by dispersion polymerization using different weight ratios of steric stabilizer poly(styrene sulfonic acid). The dispersed nanocolloidal particles ranging from 10 to 100 nm were inspected by transmission electron microscopy and particle size analyzer. The strong doping level of particles at higher weight ratios of stabilizer was analyzed by elemental analysis. The functional groups of particles were identified by Fourier transform-infrared spectra. A reduction of the conjugation length in the particles leads to the homogeneous mixture of phases which was confirmed by scanning electron microscopy and UV–visible spectra. The blue shift polaron band has confirmed the change in conjugation length of the particle. High thermal stability of particles was examined by thermogravimetry analysis.12/2014; DOI:10.1007/s40097-014-0142-x