Does Attention Deficit Hyperactivity Disorder increase the risk of suicide attempts?

New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA.
Journal of Affective Disorders (Impact Factor: 3.71). 06/2011; 133(3):595-9. DOI: 10.1016/j.jad.2011.05.008
Source: PubMed

ABSTRACT To determine if Attention Deficit Hyperactivity Disorder (ADHD) is a risk factor for suicide attempts.
Data were drawn from the National Comorbidity Replication Survey (NCS-R), a nationally representative sample of adults (N=8098).
Of the 365 adults with current ADHD, 16% attempted suicide. After controlling for the presence of comorbid disorders, logistic regression analyses revealed that the ADHD was not a not a strong predictor of suicide attempts; having one or more comorbid disorders was associated with fourfold to twelvefold elevated risk.
The small sample size of respondents with ADHD who attempted suicide significantly reduced the probability of determining which specific comorbid disorders were correlated with parasuicide.
Early treatment of ADHD and comorbidity may reduce the risk of suicide attempts and improve its prognosis.

  • [Show abstract] [Hide abstract]
    ABSTRACT: Mothers rated the frequency of suicide ideation and attempts in 925 children and adolescents with ADHD (3–16 years). Ideation and attempts were more than twice as common in ADHD-Combined type than in ADHD-Inattentive type. Ideation occurred in 19 % with ADHD-C and in 7 % with ADHD-I. Percentages for attempts were 7 % and 3 %. For children and adolescents with co-occurring sadness and oppositional defiant disorder (ODD), 46 % had ideation and 21 % had attempts (vs. 6 and 2 % for ADHD alone). For those with ideation, 78 % had ODD or sadness. For those with attempts, 84 % had ODD or sadness. Maternal ratings of aggressive, explosive, sad, and moody were significant independent predictors of suicide behavior for ADHD-C, and sad and moody were predictors for ADHD-I. All children and adolescents with ADHD should be screened for suicide ideation and attempts, and co-occurring ODD and sadness should be treated to prevent suicide behavior.
    Journal of Psychopathology and Behavioral Assessment 01/2014; DOI:10.1007/s10862-014-9451-0 · 1.55 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Pharmacotherapy of attention deficit-hyperactivity disorder (ADHD) is a well-established and effective treatment modality. However, ADHD medications are not without side effects. Understanding the prevalence of adverse events and effective management of risks associated with stimulants and other medications used to treat ADHD is central to broad applicability and effective treatment. This review discusses the literature on the prevalence of adverse events and management strategies employed. We searched online MEDLINE/PubMed and Cochrane databases for articles using several keywords relating to adverse events associated with ADHD medication management. We discuss the relevant data on the significance and prevalence of side effects and adverse events, highlight recent updates in the field, and suggest approaches to clinical management.
    Current Psychiatry Reports 10/2014; 16(10):479. DOI:10.1007/s11920-014-0479-3 · 3.05 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Suicide is among the leading causes of death among people with bipolar disorder and has gained substantial attention in the psychiatric and public health fields. However, the role of attention deficit hyperactivity disorder (ADHD) in suicide among adolescents and young adults with bipolar disorder remains unknown. Using Taiwan׳s National Health Insurance Research Database, we identified 500 adolescents and young adults from 2002 to 2008 aged between 15 and 24 years with bipolar disorder and ADHD. The sample was matched according to age and sex with 1500 (1:3) patients with bipolar disorder only and observed until the end of 2011. The patients who attempted suicide during the follow-up period were identified. Adolescents and young adults with bipolar disorder and ADHD had a greater incidence of attempted suicide than did those with bipolar disorder only (3.0% vs. 1.1%, p=0.005). After adjustment for demographic factors and psychiatric comorbidities, a Cox regression analysis determined that ADHD was an independent risk factor for attempted suicide (hazard ratio: 2.38, 95% confidence interval: 1.13-5.00) later in life among adolescents and young adults with bipolar disorder. Adolescents and young adults with bipolar disorder and ADHD had an increased likelihood of attempted suicide compared with adolescents and young adults with bipolar disorder only. Further study is required to investigate the possible pathophysiology among ADHD, bipolar disorder, and attempted suicide, and to assess whether prompt intervention for ADHD may reduce the risk of attempted suicide. Copyright © 2015 Elsevier B.V. All rights reserved.
    Journal of Affective Disorders 02/2015; 176C:171-175. DOI:10.1016/j.jad.2015.02.007 · 3.71 Impact Factor


1 Download
Available from