Rising incidence and demographics of hepatocellular carcinoma in the USA: what does it mean?

University of Massachusetts Medical School, MA, USA.
Expert review of gastroenterology & hepatology (Impact Factor: 2.55). 06/2011; 5(3):365-70. DOI: 10.1586/egh.11.20
Source: PubMed

ABSTRACT The incidence of hepatocellular carcinoma (HCC) is increasing in the USA. Traditional factors, such as hepatitis C and hepatitis B, along with new emerging trends suggest that the incidence is not only increasing, but is also likely to be under-represented in the current literature. Emerging knowledge of its incidence and epidemiology reflects an increased incidence in younger patients and certain ethnic groups. Without a clear treatment algorithm for this complex cancer, therapy and its utilization remain unclear.

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