Article

Pd-mediated new synthesis of pyrroles: their evaluation as potential inhibitors of phosphodiesterase 4.

Custom Pharmaceutical Services, Dr. Reddy's Laboratories Limited, Bollaram Road, Miyapur, Hyderabad 500 049, India.
Chemical Communications (impact factor: 6.17). 07/2011; 47(27):7779-81. DOI:10.1039/c1cc12321a pp.7779-81
Source: PubMed

ABSTRACT A sequential Pd-mediated multi-component reaction followed by Suzuki or Heck or Sonogashira coupling in a single pot has been developed for the synthesis of functionalized pyrroles as potential inhibitors of PDE4.

0 0
 · 
0 Bookmarks
 · 
74 Views
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

functionalized pyrroles
 
sequential Pd-mediated multi-component reaction
 
single pot
 
Sonogashira coupling