Article

Identification of the first human gyrovirus, a virus related to chicken anemia virus.

Institut Pasteur, Laboratory for Urgent Responses to Biological Threats, 25 rue du Docteur Roux, F-75015 Paris, France.
Journal of Virology (Impact Factor: 4.65). 06/2011; 85(15):7948-50. DOI: 10.1128/JVI.00639-11
Source: PubMed

ABSTRACT We have identified in a skin swab sample from a healthy donor a new virus that we have named human gyrovirus (HGyV) because of its similarity to the chicken anemia virus (CAV), the only previously known member of the Gyrovirus genus. In particular, this virus encodes a homolog of the CAV apoptin, a protein that selectively induces apoptosis in cancer cells. By PCR screening, HGyV was found in 5 of 115 other nonlesional skin specimens but in 0 of 92 bronchoalveolar lavages or nasopharyngeal aspirates and in 0 of 92 fecal samples.

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