Article

Hematopoietic stem cell transplantation in children.

Center for Cancer and Blood Disorders, Children's Medical Center, Dallas, TX 75235, USA.
Critical care nursing clinics of North America 06/2011; 23(2):349-76. DOI:10.1016/j.ccell.2011.02.004 pp.349-76
Source: PubMed

ABSTRACT Medical and nursing care of the hematopoietic stem cell transplantation (HSCT) recipient are complex because of the pathophysiology, HSCT process, pre-HSCT conditioning regimens, numerous medications and therapies, acute and chronic complications, adverse effects, resources involved, and environmental considerations. The HSCT process and therapies may affect any body system, requiring proficient and prioritized nursing care, possibly in an intensive care setting. Understanding the timing of potential adverse effects and complications based on engraftment will help provide competent, high-acuity care. Although autogenic and allogeneic HSCT are curative treatment options, there are numerous morbidity and/or mortality risks throughout the HSCT journey.

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Keywords

adverse effects
 
allogeneic HSCT
 
body system
 
cell transplantation
 
competent
 
environmental considerations
 
high-acuity care
 
HSCT
 
HSCT journey
 
HSCT process
 
intensive care
 
Medical
 
mortality risks
 
numerous medications
 
nursing care
 
pathophysiology
 
potential adverse effects
 
pre-HSCT conditioning regimens
 
prioritized nursing care