An alternative treatment option in tubal ectopic pregnancies with fetal heartbeat: Aspiration of the embryo followed by single-dose methotrexate administration

Obstetrics and Gynecology, Division of Reproductive Endocrinology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
Fertility and sterility (Impact Factor: 4.59). 05/2011; 96(1):79-83. DOI: 10.1016/j.fertnstert.2011.02.058
Source: PubMed


To present 13 cases of unruptured tubal ectopic pregnancies successfully treated with ultrasound-guided aspiration and local and systemic methotrexate (MTX) administration.
Case series.
University hospital.
Thirteen women with an unruptured tubal ectopic pregnancy.
Transvaginal ultrasound-guided aspiration of the tubal ectopic pregnancy followed by MTX administration into the gestational sac (half of the calculated total dose of 25 mg/m(2)) and intramuscular injection (the remaining half of the calculated total dose of 25 mg/m(2)).
Recovery of the patients, successful conservative treatment of the tubal ectopic pregnancies with preservation of the fallopian tubes.
Twelve (92%) of 13 women were successfully aborted, without need for salpingectomy or salpingostomy.
Transvaginal ultrasound-guided aspiration of fetus followed by local and systemic methotrexate administration can be safely used to treat unruptured tubal ectopic pregnancies.

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