Restless Legs Syndrome, Periodic Leg Movements, and Periodic Limb Movement Disorder in Children

Fusion Sleep Medicine Program, Atlanta, GA 30024, USA.
Pediatric Clinics of North America (Impact Factor: 2.12). 06/2011; 58(3):591-620. DOI: 10.1016/j.pcl.2011.03.005
Source: PubMed


The characteristic symptoms of restless legs syndrome (RLS) have been known for hundreds of years and were first reported in medicine in the 1600s. Clinicians must consider potential mimics, comorbid, and associated conditions when evaluating children with RLS symptoms. The traditional differentiation of RLS from periodic limb movement disorder (PLMD) is noted in children as well as adults. Because current pediatric RLS research is sparse, this article provides the most up-to-date evidence-based as well as consensus opinion-based information on the subject of childhood RLS and PLMD. Prevalence, pathophysiology, diagnosis, treatment, and clinical associations are discussed.

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