Frosted branch angiitis, neuroretinitis as initial ocular manifestation in Behçet disease.
ABSTRACT Behçet disease is an idiopathic, multisystem disorder characterized by recurrent episodes of orogenital ulceration and vasculitis of the veins and arteries of all calibers. Ocular involvement may affect the conjunctiva, sclera, uveal tract, vitreous, blood vessels, and retina. Many theories have pointed toward an autoimmune response behind its pathogenesis, which may be triggered by exposure to an infectious agent. Frosted branch angiitis is characterized by vascular inflammation, sheathing, retinal edema, and retinal hemorrhages. The disease may be idiopathic in a majority of the cases or may be associated with ocular and systemic pathology. Association between Behηet disease, Frosted branch angiitis, and neuroretinitis is not reported in literature. This uncommon combination reflects the varied systemic and ocular manifestations in Behçet disease, especially in patients who are not diagnosed and treated in time. We hereby report a case of bilateral frosted branch angiitis and neuroretinitis in a young male from Middle-east, suffering from Behçet disease.
- Retina 02/1997; 17(5):370-1. · 2.83 Impact Factor
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ABSTRACT: We report a case of Behcet's disease in a pregnant woman associated with secondary Frosted Branch Angiitis (FBA). FBA is a rare entity characterized by a florid translucent retinal perivascular sheathing of both arterioles and venules, with variable uveitis, retinal oedema and visual loss. To our knowledge, this is the first published report of FBA secondary to Behcet's disease in pregnancy.Bulletin de la Société belge d'ophtalmologie 02/2005;
Article: Frosted branch angiitis: a review.[show abstract] [hide abstract]
ABSTRACT: The purpose of this study is to present the first report of a case of primary frosted branch angiitis from the UK and to review the characteristics of this rare disease. Primary frosted branch angiitis causes characteristic florid translucent retinal perivascular sheathing of both arterioles and venules in association with variable uveitis, retinal oedema and visual loss, normally with good recovery. A total of 57 cases have been reported in the world literature. Atypical, typically focal frosted branch angiitis may also occur secondary to other causes of intraocular inflammation, especially cytomegalovirus retinitis. Primary frosted branch angiitis has a characteristic presentation but a variable course, typically affecting children or young adults. The disease is likely to represent a common immune pathway in response to multiple infective agents. The optimal treatment is unclear.Eye 06/2004; 18(5):527-33. · 1.82 Impact Factor