Article

Expression of CD25(high) regulatory T cells and PD-1 in gastric infiltrating CD4(+) T lymphocytes in patients with Helicobacter pylori infection.

Department of Medical Laboratory Science and Biotechnology, China Medical University and Hospital, No. 91 Hsueh-Shih Rd., Taichung 404, Taiwan.
Clinical and vaccine immunology: CVI (impact factor: 2.37). 05/2011; 18(7):1198-201. DOI:10.1128/CVI.00422-10 pp.1198-201
Source: PubMed

ABSTRACT We observed by flow cytometry that the frequency of both gastric infiltrating Tregs and PD-1-positive CD4 T cells is correlated with the density of Helicobacter pylori, suggesting that cellular immunity against this pathogen is inhibited.

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Keywords

cellular immunity
 
flow cytometry
 
gastric
 
Helicobacter pylori
 
pathogen
 
PD-1-positive CD4 T cells
 
Tregs