Leiomyosarcoma of the breast: A case report and review of the literature about therapeutic management
ABSTRACT We experienced a leiomyosarcoma of the breast in an 18-year-old female. No specific treatment has been established. In order to clarify appropriate therapeutic management methods, the limited data available from our and previous case reports were assessed. A leiomyosarcoma of the breast must be excised with a negative margin. If the tumor size is large and an adequate margin, greater than 3-cm margin around the excised tumor, is not achieved due to anatomical constraints, radiotherapy may be indicated.
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ABSTRACT: Primary leiomyosarcoma is a disease with <50 documented cases in the literature worldwide. The standard of care for these tumors has not been established. Physicians who have seen these cases in the past have used wide local excision with or without adjunctive chemo-radiation therapy. We review the literature concerning the mainstay of treatment as well as present a new case of an adolescent with primary leiomyosarcoma.01/2014; 2014(1). DOI:10.1093/jscr/rjt121