Leiomyosarcoma of the breast: A case report and review of the literature about therapeutic management

Department of Breast and Endocrine Surgery, Osaka Kosei-Nenkin Hospital, and Department of Breast and Endocrine Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Breast (Edinburgh, Scotland) (Impact Factor: 2.38). 04/2011; 20(5):389-93. DOI: 10.1016/j.breast.2011.03.001
Source: PubMed


We experienced a leiomyosarcoma of the breast in an 18-year-old female. No specific treatment has been established. In order to clarify appropriate therapeutic management methods, the limited data available from our and previous case reports were assessed. A leiomyosarcoma of the breast must be excised with a negative margin. If the tumor size is large and an adequate margin, greater than 3-cm margin around the excised tumor, is not achieved due to anatomical constraints, radiotherapy may be indicated.

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    • "Sarcomas of female breast are very rare. To date, approximately 20 cases of primary leiomyosarcoma of the breast have been reported [1]. The most common benign tumor of the breast is fibroadenoma (FA), in which both glandular and fibrous tissues are components of one tumor. "
    12/2014; 20. DOI:10.1016/j.ehpc.2014.11.007
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    • "EP commonly occurs in stomach and duodenum, but EP in ileum is very rare. Further, large EP of ileum causing intussusceptions and obstructive ileus has rarely been reported [1]. A 68-year-old man was emergently admitted to our hospital because of abdominal pain and nausea. "
    06/2014; 20(2). DOI:10.1016/j.ehpc.2014.09.006
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    • "leiomyosarcoma have been postmenopausal, typically in the six-eighth decade. However, our patient is one of the two reported cases [8] of a young girl in her late teens to be diagnosed with a primary breast sarcoma. As with other sarcomas, prior chemotherapy for either a primary breast carcinoma or any other malignancy is a risk factor reported in the literature [6]. "
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    ABSTRACT: Leiomyosarcoma of the breast is a rare neoplasm, primarily reported in older women. Only 44 cases have been reported in world literature and to the best of our knowledge, no case has been reported from India till date. We report a case of primary breast leiomyosarcoma in an adolescent girl who underwent a lumpectomy for rapidly increasing lump in the left breast. Here we report the histological findings and immunohistochemical profile of this entity, along with a review of existing literature.
    03/2012; 2012(2):491984. DOI:10.1155/2012/491984
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