Article

Effect of viscosity of enteral nutrient on gut motility and hormone secretion in dogs.

Division of Biological Regulation and Oncology, Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Hepato-gastroenterology (impact factor: 0.66). 58(105):36-41. pp.36-41
Source: PubMed

ABSTRACT Our aim was to study the effect of the viscosity of enteral nutrient solutions on upper gut motility and gut hormone secretion.
We used 5 beagle dogs equipped with strain gauge force transducers to measure upper gastrointestinal motility. Upper gut motility and gut hormone secretion were compared across 6 experimental conditions; control (oral solid meal), liquid-120, liquid-5 (liquid enteral nutrients administered for 120 and 5 min, respectively), low, middle, and high viscosity conditions.
The magnitude of receptive relaxation was decreased in the liquid-120 compared to control, but this decrease was reversed with the increase of viscosity. The duration of the postprandial contractions in the proximal jejunum was decreased in the liquid-5 compared to the control, but this decrease was reversed in the middle and high viscosity conditions (p < 0.05). Rapid increase in plasma concentrations of gastric inhibitory polypeptide observed in the liquid-5 compared to the control was reversed in the low, middle, and high viscosity conditions.
Although patterns of upper gut motility and gut hormone secretion after liquid enteral nutrients were considerably altered compared to those after solid meal ingestion, increasing the viscosity of liquid enteral nutrients reversed those altered patterns.

0 0
 · 
0 Bookmarks
 · 
32 Views
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

5 beagle dogs
 
6 experimental conditions
 
enteral nutrient solutions
 
gastric inhibitory polypeptide
 
gut hormone secretion
 
liquid enteral nutrients
 
liquid-5
 
low
 
measure upper gastrointestinal motility
 
oral solid meal
 
plasma concentrations
 
postprandial contractions
 
proximal jejunum
 
receptive relaxation
 
solid meal ingestion
 
strain gauge force transducers
 
upper gut motility
 
viscosity
 
viscosity conditions