Liver Transplantation for Giant Hepatic Angiomyolipoma

Departments of Surgery (Division of Transplant Surgery), University of California San Francisco, San Francisco, CA.
Liver Transplantation (Impact Factor: 3.79). 08/2011; 17(8):985-6. DOI: 10.1002/lt.22310
Source: PubMed
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Available from: Parsia A Vagefi, Mar 13, 2015
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    ABSTRACT: Hepatic angiomyolipomas (AMLs) are typically benign tumors containing varying amounts of smooth muscle cells, adipose tissue, and vessels, and are commonly found in the kidney and occasionally in the liver. The preoperative diagnosis of hepatic AML is primarily made from imaging and fine-needle aspiration biopsy results, though limited experience for such diagnoses can result in misdiagnosis. Some uncommon features of hepatic AML have been reported in the literature without an objective or qualitative consensus. As the majority of cases are benign, conservative treatment of AMLs is recommended. However, in rare cases, liver transplantation has been implemented. Only five cases of malignant hepatic AML have been reported. We report a rare case of recurrent posthepatectomy malignant hepatic AML that was misdiagnosed as liver cancer in a 37-year-old woman, which was treated by liver transplantation. The imaging and pathologic findings are presented in order to provide a more concise description to aid in future diagnoses.
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