Article

Inflammatory bowel disease characteristics in Hispanic children in Texas.

Department of Pediatrics, Baylor College of Medicine, Houston, TX77030, USA.
Inflammatory Bowel Diseases (impact factor: 4.86). 03/2011; 18(3):546-54. DOI:10.1002/ibd.21698 pp.546-54
Source: PubMed

ABSTRACT Inflammatory bowel disease (IBD) has a wide spectrum and variability among different ethnic groups. We aimed to evaluate disease characteristics in the pediatric Hispanic population, which has not been well studied.
We identified patients <18 years old seen at Texas Children's Hospital (TCH) and diagnosed with IBD between 2004 and 2009. We compared them with their White, African American, and "other" counterparts with regard to their demographics, disease characteristics, and initial therapy.
There were a total of 399 patients with IBD: 211 (52.9%) White, 67 (16.8%) African American, 53 (13.3%) Hispanic, and 68 (17%) "other." Crohn's disease (CD) was the most common IBD type among all groups; however, Hispanics had the highest proportion of patients with ulcerative colitis (UC) and IBD-unclassified (IBD-U). There was male predominance in all groups except African Americans. Hispanics had the highest percentage of Medicaid coverage (P < 0.01) and none of the Hispanics had a first-degree relative with IBD. They had a younger age at diagnosis but a similar duration of symptoms prior to diagnosis. Hispanics had less failure to thrive and a higher body mass index (BMI) Z-score. Hispanics with CD more often received systemic steroids while those with UC and IBD-U were more often treated with local steroids (P < 0.01), oral 5-aminosalicylate (P < 0.01), and less often received immunomodulators or biologics (P = 0.05).
We demonstrate differences in disease characteristics between Hispanics and other ethnicities with IBD. Further epidemiologic studies are needed, including longer-term follow-up, to better define the burden of illness in Hispanics.

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    Article: Investigation of small bowel in pediatric Crohn's disease.
    Giovanni Di Nardo, Marina Aloi, Salvatore Oliva, Fortunata Civitelli, Emanuele Casciani, Salvatore Cucchiara
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    Inflammatory Bowel Diseases 01/2012; 18(9):1760-76. · 4.86 Impact Factor
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

African American
 
African Americans
 
common IBD type
 
Crohn's disease
 
different ethnic groups
 
disease characteristics
 
epidemiologic studies
 
higher body mass index
 
Hispanics
 
Inflammatory bowel disease
 
initial therapy
 
Medicaid coverage
 
oral 5-aminosalicylate
 
patients <18 years old
 
pediatric Hispanic population
 
similar duration
 
systemic steroids
 
Texas Children's Hospital
 
wide spectrum
 
younger age