Article

Criminal conviction, impulsivity, and course of illness in bipolar disorder.

Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 1941 East Road, Houston, TX 77054, USA.
Bipolar Disorders (impact factor: 5.29). 03/2011; 13(2):173-81. DOI:10.1111/j.1399-5618.2011.00900.x pp.173-81
Source: PubMed

ABSTRACT Criminal behavior in bipolar disorder may be related to substance use disorders, personality disorders, or other comorbidities potentially related to impulsivity. We investigated relationships among impulsivity, antisocial personality disorder (ASPD) or borderline personality disorder symptoms, substance use disorder, course of illness, and history of criminal behavior in bipolar disorder.
A total of 112 subjects with bipolar disorder were recruited from the community. Diagnosis was by Structured Clinical Interview for DSM-IV (SCID-I and SCID-II); psychiatric symptom assessment by the Change version of the Schedule for Affective Disorders and Schizophrenia (SADS-C); severity of Axis II symptoms by ASPD and borderline personality disorder SCID-II symptoms; and impulsivity by questionnaire and response inhibition measures.
A total of 29 subjects self-reported histories of criminal conviction. Compared to other subjects, those with convictions had more ASPD symptoms, less education, more substance use disorder, more suicide attempt history, and a more recurrent course with propensity toward mania. They had increased impulsivity as reflected by impaired response inhibition, but did not differ in questionnaire-measured impulsivity. On logit analysis, impaired response inhibition and ASPD symptoms, but not substance use disorder, were significantly associated with criminal history. Subjects convicted for violent crimes were not more impulsive than those convicted for nonviolent crimes.
In this community sample, a self-reported history of criminal behavior is related to ASPD symptoms, a recurrent and predominately manic course of illness, and impaired response inhibition in bipolar disorder, independent of current clinical state.

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Keywords

29 subjects self-reported histories
 
Affective Disorders
 
antisocial personality disorder
 
ASPD symptoms
 
Axis II symptoms
 
bipolar disorder
 
borderline personality disorder SCID-II symptoms
 
borderline personality disorder symptoms
 
community sample
 
criminal conviction
 
criminal history
 
current clinical state
 
personality disorders
 
predominately manic course
 
questionnaire-measured impulsivity
 
recurrent course
 
self-reported history
 
substance use disorder
 
substance use disorders
 
suicide attempt history