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[A case of early recognized Wegener's granulomatosis with renal involvement. Insights for early diagnosis].

Agnieszka Matuszewska, Maria Misterska-Skóra, Piotr Wiland

Klinika Reumatologii i Chorób Wewnetrznych Akademickiego Szpitala Klinicznego im. Mikulicza-Radeckiego, ul. Borowska 213, 50-556 Wrocław.

Journal Article: Annales Academiae Medicae Stetinensis 01/2010; 56(1):41-4; discussion 44.

Abstract

Systemic necrotic and granulomatous vasculitis presents with vascular involvement in almost every organ, manifesting with stenosis, ischemia, infarction, or hemorrhage. The clinical picture depends on the kind and size of the involved vessels and on the activity of the inflammatory process. Wegener's granulomatosis is a necrotic, granulomatous inflammation of small vessels of the upper and lower airways and kidneys. We present the case of a 25-year-old male in whom the definitive diagnosis of Wegener's granulomatosis was achieved within five weeks from onset. Among the first symptoms were microinfarcts localized in the fingertips and the nail matrix; their nature was investigated with capillaroscopy.

Source: PubMed

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Keywords

clinical picture
 
definitive diagnosis
 
granulomatous vasculitis presents
 
inflammatory process
 
involved vessels
 
ischemia
 
necrotic
 
small vessels
 
Systemic necrotic
 
upper
 
vascular involvement
 
Wegener's granulomatosis