Article

Recurrent neural network for non-smooth convex optimization problems with application to the identification of genetic regulatory networks.

IEEE Transactions on Neural Networks (impact factor: 2.95). 03/2011; 22(5):714-26. DOI:10.1109/TNN.2011.2109735 pp.714-26
Source: PubMed

ABSTRACT A recurrent neural network is proposed for solving the non-smooth convex optimization problem with the convex inequality and linear equality constraints. Since the objective function and inequality constraints may not be smooth, the Clarke's generalized gradients of the objective function and inequality constraints are employed to describe the dynamics of the proposed neural network. It is proved that the equilibrium point set of the proposed neural network is equivalent to the optimal solution of the original optimization problem by using the Lagrangian saddle-point theorem. Under weak conditions, the proposed neural network is proved to be stable, and the state of the neural network is convergent to one of its equilibrium points. Compared with the existing neural network models for non-smooth optimization problems, the proposed neural network can deal with a larger class of constraints and is not based on the penalty method. Finally, the proposed neural network is used to solve the identification problem of genetic regulatory networks, which can be transformed into a non-smooth convex optimization problem. The simulation results show the satisfactory identification accuracy, which demonstrates the effectiveness and efficiency of the proposed approach.

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Keywords

Clarke's generalized gradients
 
convex inequality
 
dynamics
 
existing neural network models
 
genetic regulatory networks
 
inequality constraints
 
Lagrangian saddle-point theorem
 
larger class
 
linear equality constraints
 
neural network
 
non-smooth convex optimization problem
 
non-smooth optimization problems
 
objective function
 
original optimization problem
 
proposed approach
 
proposed neural network
 
recurrent neural network
 
simulation results
 
weak conditions
 

Long Cheng