Article

Self-assembled nanospheres as a novel delivery system for taxol: A molecular hydrogel with nanosphere morphology

Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, PR China.
Chemical Communications (Impact Factor: 6.72). 03/2011; 47(15):4439-41. DOI: 10.1039/c1cc10506j
Source: PubMed

ABSTRACT Here we reported on the first example of a Folic acid-based molecular hydrogel with nanosphere morphology as a delivery system for Taxol.

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    • "Our group has reported several molecular hydrogelators of taxol derivatives [21] [22]. During the preparation of aqueous solutions of taxol derivatives, we occasionally found that taxol derivatives would undergo an ester bond hydrolysis process to release the original taxol molecule, thus leading to the formation of molecular hydrogels. "
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