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[Musculoskeletal symptoms in systemic lupus erythematosus and their differential diagnosis with rheumatoid arthritis].

Piotr Wiland

Katedra i Klinika Chorób Wewnetrznych i Reumatologii Akademii Medycznej we Wrocławiu ul. Borowska 213, 50-556 Wrocław.

Journal Article: Annales Academiae Medicae Stetinensis 01/2010; 56 Suppl 1:40-4.

Abstract

The musculoskeletal system is involved in nearly all patients with systemic lupus erythematosus (SLE). Transient arthralgias and arthritis are commonly observed. Some patients develop chronic synovitis, which can result in deformities of the joints known as Jaccoud's arthropathy and seen in 10-35% of patients with SLE. Many patients with SLE are initially misdiagnosed with rheumatoid arthritis (RA). Differentiation of SLE from RA can be done with diagnostic imaging, tests for anticitrullinated peptide antibodies (anti-CCP) and rheumatoid factor, and analysis of the clinical picture. It is important to undertake the differential diagnosis not only in early arthritis but also at later stages of the disease when new clinical symptoms have cast doubt on the diagnosis.

Source: PubMed

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Keywords

anticitrullinated peptide antibodies
 
arthritis
 
diagnostic imaging
 
differential diagnosis
 
Jaccoud's arthropathy
 
joints
 
new clinical symptoms
 
patients
 
rheumatoid arthritis
 
rheumatoid factor
 
SLE
 
systemic lupus erythematosus
 
Transient arthralgias