Article

Antimelanogenic and antioxidative properties of Bifidobacterium bifidum.

Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan, ROC.
Archives for Dermatological Research (impact factor: 2.28). 03/2011; 303(7):527-31. DOI:10.1007/s00403-011-1135-y pp.527-31
Source: PubMed

ABSTRACT Various skin hyperpigmentation disorders consist in accumulation and overproduction of melanin. In this report, we investigated the melanogenesis inhibitory and antioxidant effects of Bifidobacterium bifidum culture filtrate. The results revealed that B. bifidum culture filtrate effectively suppresses murine tyrosinase activity and decreases the amount of intracellular melanin in a dose-dependent manner. Additionally, the bacterial culture filtrate-scavenged DPPH and ABTS radicals, and shows potent-reducing power in a dose-dependent pattern. Our results expand the application of B. bifidum culture filtrate in the development and research of skin-whitening ingredients.

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Keywords

accumulation
 
B. bifidum culture filtrate
 
bacterial culture filtrate-scavenged DPPH
 
Bifidobacterium bifidum culture filtrate
 
dose-dependent manner
 
intracellular melanin
 
melanin
 
melanogenesis inhibitory
 
potent-reducing power
 
skin-whitening ingredients
 
Various skin hyperpigmentation disorders