Brief Report: Symptom Onset Patterns and Functional Outcomes in Young Children with Autism Spectrum Disorders

Pediatrics and Developmental Neuroscience Branch, National Institute of Mental Health, Bethesda, MD 20892-1255, USA.
Journal of Autism and Developmental Disorders (Impact Factor: 3.06). 03/2011; 41(12):1727-32. DOI: 10.1007/s10803-011-1203-3
Source: PubMed

ABSTRACT This study examined the relationship between onset status and current functioning using a recently proposed onset classification system in 272 young children with autism spectrum disorder (ASD). Participants were classified into one of the following groups, based on parent report using the Autism Diagnostic Interview--Revised: Early Onset (symptoms by 12 months, no loss), Delay + Regression (symptoms by 12 months plus loss), Plateau (no early symptoms or loss), and Regression (no early symptoms, followed by loss). Findings indicate that current functioning does not differ according to onset pattern, calling into question the use of onset categorizations for prognostic purposes in children with ASD.

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