Article

A twist on admixture mapping

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Nature Genetics (Impact Factor: 29.65). 03/2011; 43(3):178-9. DOI: 10.1038/ng0311-178
Source: PubMed

ABSTRACT A new study uses genome-wide SNP genotypes to identify a subset of children undergoing therapy for acute lymphoblastic leukemia that are at increased risk for relapse. Borrowing from the classical approach of admixture mapping, the work shows how genome-wide assessment of genetic ancestry can be used as a biomarker for disease outcome.

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