Article

Iloprost in the management of peripheral arterial disease in patients with diabetes mellitus.

Sezione Piede Diabetico, Unità Operativa Malattie del Metabolismo e Diabetologia, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italia.
Minerva cardioangiologica 02/2011; 59(1):101-8. pp.101-8
Source: PubMed

ABSTRACT Diabetic complications in the lower extremities, especially those secondary to diabetic macroangiopathy, have increasingly become a clinical emergency, given the high prevalence and progression of the disease. Until recently, the only approach to treating advanced stage disease was medical therapy and major amputation; however, the advent of revascularization procedures has radically improved the prognosis of patients with critical lower limb ischemia. In this setting, iloprost holds a dual position: as first-choice therapy in patients ineligible for revascularization and as complementary therapy in candidates for surgical or endovascular revascularization.

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Keywords

advent
 
clinical emergency
 
complementary therapy
 
critical lower limb ischemia
 
Diabetic complications
 
diabetic macroangiopathy
 
dual position
 
major amputation
 
patients
 
patients ineligible
 
revascularization procedures
 
stage disease
 

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