50 Years Later: Remembering the Paper

Stanford Institute of Stem Cell Biology and Regenerative Medicine, Stanford, CA, USA.
Radiation Research (Impact Factor: 2.91). 02/2011; 175(2):143-4. DOI: 10.2307/41061202
Source: PubMed
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    • "Till and McCulloch published a seminal paper, which was published in its original form again this year, providing a quantitative method for analyzing hematopoietic cells capable of continued proliferation in vivo and providing a singularly important observation that single cells could give rise to all hematopoietic lineages in vivo (Till and McCulloch, 1961, 2011; Weissman, 2011). Supralethally irradiated mice were injected with nucleated bone marrow cells and the spleen colony-forming units quantified. "
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