Article

Short-term prognosis of adaptive servo-ventilation therapy in patients with heart failure.

Department of Cardiovascular and Respiratory Medicine, Akita University Graduate School of Medicine, Akita, Japan.
Circulation Journal (impact factor: 3.77). 01/2011; 75(3):710-2.
Source: PubMed

ABSTRACT This study tested the hypothesis that adaptive servo-ventilation (ASV) therapy improves the prognosis of heart failure (HF) patients, regardless of the severity of sleep-disordered breathing (SDB).
88 consecutive patients were divided into 4 groups based on ASV therapy and SDB severity. The incidence of HF, brain natriuretic peptide (BNP) levels, and left ventricular ejection fraction (LVEF) were followed for 12 months. Fewer HF events, together with an increase in LVEF and a decrease in BNP, occurred in ASV-treated patients with both non-to-mild and moderate-to-severe SDB.
ASV therapy improves the short-term prognosis in HF-patients, regardless SDB severity.

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Keywords

4 groups
 
88 consecutive patients
 
adaptive servo-ventilation
 
ASV
 
ASV therapy
 
ASV-treated patients
 
BNP
 
brain natriuretic peptide
 
heart failure
 
HF
 
HF events
 
HF-patients
 
LVEF
 
non-to-mild
 
SDB severity
 
severity
 
short-term prognosis
 
sleep-disordered breathing
 
ventricular ejection fraction