Radiographic features of intraluminal leiomyosarcoma of the inferior vena cava: an atypical case report
ABSTRACT We encountered a 74-year-old woman with a chief complaint of progressive right-sided back pain for more than 1 month. Physical examination and laboratory tests revealed no abnormalities. Multislice computed tomography (MSCT) showed dilatation of the inferior vena cava (IVC). An intraluminal mass of about 8.1 × 5.5 × 3.6 cm in size was found in the IVC, with big central necrosis and irregular peripheral enhancement. The tumor arose from the IVC just beneath the renal vein and reached the iliac bifurcation. Cavography demonstrated a filling defect with complete occlusion of the IVC and extensive collateral circulation. The patient underwent complete resection of tumor and vascular prosthetic graft. Pathological diagnosis was leiomyosarcoma. Because of its low incidences and atypical appearance, we highlight the significance of the imaging feature in its diagnosis in this article.
Article: Solución al caso 49Radiología 09/2013; 55(5):459–461. DOI:10.1016/j.rx.2011.09.013
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ABSTRACT: A 72-year-old Caucasian man presenting with non-specific upper abdominal pain had asymmetric soft tissue thickening of the small bowel wall on computed tomography (CT), which was pathologically proven to be leiomyosarcoma (LMS). At the same time point patient had incidentally but retrospectively detected lesion in IVC on CT scan which was subsequently imaged with PET/CT and MRI and was histologically proven to be also LMS. We present clinical and imaging features along with pedigree of this unique case of synchronous primary LMS involving the small bowel and inferior vena cava in a patient with RB1 gene mutation and a significant family history of multiple malignancies. To our knowledge, the synchronous primary LMS at two different sites has not been described. Clinicians and radiologists should keep in mind the possibility of a synchronous primary LMS in patients with genetic predisposition before making the diagnosis of a metastatic lesion or other malignancy as localized primary tumors remain potentially curable, whereas metastatic sarcoma is most often incurable.Abdominal Imaging 05/2012; 39(1). DOI:10.1007/s00261-012-9904-4 · 1.73 Impact Factor