Article

The promise of optogenetics in cell biology: interrogating molecular circuits in space and time

Department of Cellular and Molecular Pharmacology and the Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, USA.
Nature Methods (Impact Factor: 25.95). 01/2011; 8(1):35-8. DOI: 10.1038/nmeth.f.326
Source: PubMed

ABSTRACT Optogenetic modules offer cell biologists unprecedented new ways to poke and prod cells. The combination of these precision perturbative tools with observational tools, such as fluorescent proteins, may dramatically accelerate our ability to understand the inner workings of the cell.

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