Lower levels of physical activity in childhood associated with adult depression.
ABSTRACT Emerging evidence indicates that early life exposures influence adult health outcomes and there is cause to hypothesise a role for physical activity (PA) in childhood as a protective factor in adult depression. This study aimed to investigate the association between self-reported levels of PA in childhood and self-reported depressive illness. Lifetime depression and levels of physical activity (low/high) in childhood (<15 yr) were ascertained by self-report in 2152 adults (20-97 yr) participating in an ongoing epidemiological study in south-eastern Australia. Data were collected between 2000 and 2006. In this sample, 141 women (18.9%) and 169 men (12.0%) reported ever having a depressive episode. Low PA in childhood was associated with an increased risk of reporting depression in adulthood (OR=1.70, 95%CI=1.32-2.17, p<0.001). Adjustment for age, gender and adult PA attenuated the relationship somewhat (OR=1.35, 95%CI=1.01-1.78, p=0.04), however further adjustment for SES or country of birth did not affect this relationship. In this community-based study, lower levels of self-reported PA in childhood were associated with a 35% increase in odds for self-reported depression in adulthood. These results are consistent with the hypothesis that lower levels of PA in childhood may be a risk factor for adult depression.
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Article: Lifestyle medicine for depression.[Show abstract] [Hide abstract]
ABSTRACT: The prevalence of depression appears to have increased over the past three decades. While this may be an artefact of diagnostic practices, it is likely that there are factors about modernity that are contributing to this rise. There is now compelling evidence that a range of lifestyle factors are involved in the pathogenesis of depression. Many of these factors can potentially be modified, yet they receive little consideration in the contemporary treatment of depression, where medication and psychological intervention remain the first line treatments. "Lifestyle Medicine" provides a nexus between public health promotion and clinical treatments, involving the application of environmental, behavioural, and psychological principles to enhance physical and mental wellbeing. This may also provide opportunities for general health promotion and potential prevention of depression. In this paper we provide a narrative discussion of the major components of Lifestyle Medicine, consisting of the evidence-based adoption of physical activity or exercise, dietary modification, adequate relaxation/sleep and social interaction, use of mindfulness-based meditation techniques, and the reduction of recreational substances such as nicotine, drugs, and alcohol. We also discuss other potential lifestyle factors that have a more nascent evidence base, such as environmental issues (e.g. urbanisation, and exposure to air, water, noise, and chemical pollution), and the increasing human interface with technology. Clinical considerations are also outlined. While data supports that some of these individual elements are modifiers of overall mental health, and in many cases depression, rigorous research needs to address the long-term application of Lifestyle Medicine for depression prevention and management. Critically, studies exploring lifestyle modification involving multiple lifestyle elements are needed. While the judicious use of medication and psychological techniques are still advocated, due to the complexity of human illness/wellbeing, the emerging evidence encourages a more integrative approach for depression, and an acknowledgment that lifestyle modification should be a routine part of treatment and preventative efforts.BMC Psychiatry 04/2014; 14(1):107. · 2.23 Impact Factor
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ABSTRACT: This study examined whether Castelli risk indexes 1 (total / high-density lipoprotein (HDL) cholesterol) and 2 (low densitity lipoproptein (LDL) / HDL cholesterol) and other shared metabolic disorders might underpin the pathophysiology of the metabolic syndrome, major depression or bipolar disorder. This cross-sectional study examined 92 major depressed, 49 bipolar depressed and 201 normal controls in whom the Castelli risk indexes 1 and 2 and key characteristics of the metabolic syndrome, i.e. waist / hip circumference, body mass index (BMI); systolic / diastolic blood pressure; total cholesterol, low-density lipoprotein (LDL) and HDL cholesterol, triglycerides; insulin, glucose, hemoglobin A1c (HbA1c); and homocysteine were assessed. Castelli risk indexes 1 and 2 were significantly higher in major depressed patients than in bipolar disorder patients and controls. There were no significant differences in waist or hip circumference, total and LDL cholesterol, triglycerides, plasma glucose, insulin, homocysteine and HbA1c between depression and bipolar patients and controls. Bipolar patients had a significantly higher BMI than major depressed patients and normal controls. Major depression is accompanied by increased Castelli risk indexes 1 and 2, which may be risk factors for cardiovascular disease. Other key characteristics of the metabolic syndrome, either metabolic biomarkers or central obesity, are not necessarily specific to major depression or bipolar disorder.Life sciences 03/2014; · 2.56 Impact Factor
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ABSTRACT: Objectives The objective of this study was to investigate changes in use of time when undertaking a structured exercise program. Design This study used a randomised, multi-arm, controlled trial design. Methods A total of 129 insufficiently active adults aged 18-60 years were recruited and randomly allocated to one of three groups, a Moderate or Extensive six-week exercise group (150 and 300 additional minutes of exercise per week, respectively) or a Control group. Prescribed exercise was accumulated through both group and individual sessions. Use of time was measured at baseline and end-program using the Multimedia Activity Recall for Children and Adults, a computerised 24-hour recall instrument. Daily minutes of activity in activity domains and energy expenditure zones were determined. Results Relative to changes in the control group, daily time spent in the Physical Activity [F (2, 108) = 20.21, p < 0.001] and Active Transport [F (2, 108) = 3.71, p = 0.03] time use domains significantly increased in the intervention groups by 21-45 minutes/day. Comparatively, the intervention groups spent significantly less time watching television [F (2, 108) = 5.02, p = 0.008; -50-52 min/day], relative to Controls. Additionally, time spent in the moderate to vigorous energy expenditure zone had significantly increased in the intervention groups by end-program [F (2, 108) = 6.35, p = 0.002; 48-50 min/day], relative to Controls. Conclusion This study is the first to comprehensively map changes in time use across an exercise program. The results suggest that exercise interventions should be mindful not only of compliance but of “isotemporal displacement” of behaviours.Journal of Science and Medicine in Sport. 01/2014;