MicroRNAs in a Cardiac Loop: Progenitor or Myocyte?

Department of Medicine, University of California San Diego, La Jolla, 92093, USA.
Developmental Cell (Impact Factor: 9.71). 12/2010; 19(6):787-8. DOI: 10.1016/j.devcel.2010.11.015
Source: PubMed


Like transcription factors, microRNAs are emerging as regulators of cell fate decisions. In this issue, Wang et al. (2010) identify a critical microRNA pathway under the control of Bmp signaling that promotes outflow tract myocardial differentiation from cardiac progenitors in vivo.

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