Article

Polyarteritis nodosa in a patient with type 1 autoimmune hepatitis.

Division of Gastroenterology and Hepatology and Rheumatology, 2nd Propedeutic Department of Internal Medicine, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Southern medical journal (impact factor: 0.92). 01/2011; 104(1):49-52. DOI:10.1097/SMJ.0b013e3181fd0be6 pp.49-52
Source: PubMed

ABSTRACT Polyarteritis nodosa is a systemic necrotizing vasculitis that affects small- and medium-sized arteries. Liver involvement in patients with polyarteritis nodosa has been described, and ranges from asymptomatic elevation of aminotransferases to hepatic aneurysm rupture. We describe the case of a patient with type 1 autoimmune hepatitis and compensated liver cirrhosis who developed classic polyarteritis nodosa, complicated with cytomegalovirus and repeated urinary tract infections. After a long bedridden hospitalization, the patient's condition was stabilized. She is currently in good health, with well-controlled blood pressure, and stable kidney and liver function. To our knowledge, this is the first case report in the literature with concurrent appearance of both diseases.

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Keywords

aminotransferases
 
classic polyarteritis nodosa
 
diseases
 
first case report
 
good health
 
medium-sized arteries
 
patient's condition
 
patients
 
polyarteritis nodosa
 
ranges
 
stable kidney
 
systemic necrotizing vasculitis
 
type 1 autoimmune hepatitis
 
urinary tract infections
 
well-controlled blood pressure