Article

Rituximab-induced subacute interstitial pneumonitis: a case report and review of literature.

Department of Medical Oncology, M. S. Ramaiah Medical College, Bangalore 560 054, India.
Journal of cancer research and therapeutics (impact factor: 0.83). 6(3):344-6. DOI:10.4103/0973-1482.73356
Source: PubMed

ABSTRACT Rituximab is a chimeric anti-CD20 monoclonal antibody used to treat CD20+ non-Hodgkin's lymphoma (NHL). Some pulmonary adverse reactions such as cough, rhinitis, bronchospasm and dyspnea are relatively common. Severe respiratory conditions like cryptogenic organizing pneumonia, interstitial pneumonitis have rarely been reported. We present a case of interstitial pneumonitis in a patient who was treated with R-CHOP for extranodal NHL. He responded to the steroids.

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Murali Subramanian