Synthesis and anti-HCV activity of a new 2'-deoxy-2'-fluoro-2'-C-methyl nucleoside analogue.
Department of Chemistry, Zhengzhou University, Zhengzhou, Henan Province, PR China.Bioorganic & medicinal chemistry letters (impact factor: 2.65). 12/2010; 20(24):7297-8. DOI:10.1016/j.bmcl.2010.10.076 pp.7297-8
ABSTRACT 2'-Deoxy-2'-fluoro-2'-C-methyl nucleoside analogue 4 was designed and synthesized. Initial biological studies indicated that this compound showed promising activity against HCV replication.
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