Article

The impact of psychological stress on wound healing: methods and mechanisms.

Department of Psychology, The Ohio State University, 225 Psychology Building, 1835 Neil Avenue, Columbus, OH 43210, USA.
Immunology and allergy clinics of North America (Impact Factor: 2.22). 02/2011; 31(1):81-93. DOI: 10.1016/j.iac.2010.09.010
Source: PubMed

ABSTRACT Converging and replicated evidence indicates that psychological stress can modulate wound-healing processes. This article reviews the methods and findings of experimental models of wound healing. Psychological stress can have a substantial and clinically relevant impact on wound repair. Physiologic stress responses can directly influence wound-healing processes. Furthermore, psychological stress can indirectly modulate the repair process by promoting the adoption of health-damaging behaviors. Translational work is needed to develop innovative treatments able to attenuate stress-induced delays in wound healing.

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Available from: Jean-Philippe Gouin, Apr 21, 2015
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